CHOP antibody
FNab01668
Catalogue No.
- Synonyms:
- C/EBP homologous protein, C/EBP homologous protein 10, CEBPZ, CHOP, CHOP 10, CHOP; GADD153, CHOP10, DDIT 3, DDIT3, GADD153
- Host:
- Mouse
- Reactivity:
- Human, Mouse, Rat
- Isotype:
- IgG2a
- Tested Application:
- ELISA, WB
Product Information
- Product Name
- CHOP antibody
- Catalogue No.
- FNab01668
- Size
- 100µg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Host
- Mouse
- Clonality
- monoclonal
- Isotype
- IgG2a
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
- CHOP, also known as GADD153 or DDIT3, is a highly conserved gene in both the structural and regulatory regions to hamster gene.Imposed by unfolded and malfolded proteins, CHOP is significantly induced by ER stress, deficiency of CHOP prevents cell from ER stress. CHOP is considered a proapoptotic marker of ER stress dependent cell death. CHOP acts as a dominant-negative inhibitor of the transcription factor C/EBP and LAP by forming a heterodimer. It may play an important role in the malignant transformation of nevus to melanoma.
Immunogen Information
- Immunogen
- DNA-damage-inducible transcript 3
- Synonyms
- C/EBP homologous protein, C/EBP homologous protein 10, CEBPZ, CHOP, CHOP 10, CHOP; GADD153, CHOP10, DDIT 3, DDIT3, GADD153
- Observed MW
- 30 kDa
Application
- Tested Application
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:5000
Uniprot information
- UniProt ID
- P35638
Images
- Image 4
-
Various lysates were subjected to SDS PAGE followed by western blot with FNab01668(CHOP Antibody) at dilution of 1:1000